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List of Studies

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The table below shows the current NIMH studies, both released and in-process. For in-process studies that are not yet released for distribution, the table shows the expected number of subjects, marked with an orange superscript.

Study Title Distributions PIs Grants Sites Subjects
0 NIMH Bipolar Genetics Initiative Bipolar Disorder DEPAULO, MCMAHON, NURNBERGER, REICH

5U01MH046282, 5U01MH046280, 5U01MH046274

10, 12 1353
0 NIMH Schizophrenia Genetics Initiative Schizophrenia CLONINGER, KAUFMANN, TSUANG

5U01MH046318, 5U01MH046276, 5U01MH046289

30, 31, 32 877
0 NIMH Alzheimers Genetics Initiative Alzheimer's Disease ALBERT, BASSETT, GO

5U01MH046281, 5U01MH046290, 5U01MH046373

50, 51, 52 1411
1 A Collaborative Genomic Study of Bipolar Disorder Bipolar Disorder BERRETTINI, BYERLEY, CORYELL, DEPAULO, MCMAHON, NURNBERGER

R01MH059545

20, 21, 22, 23, 24, 25, 26, 28, 29 1880
2 Molecular Genetics of Bipolar Disorder Bipolar Disorder BARON

R01MH059602

15, 16 843
3 Genetic Linkage Study of Schizophrenia Schizophrenia TSUANG

R01MH059624

34, 35 2328
4 Collaborative Linkage Study of Autism Autism FOLSTEIN, PIVEN

R01MH055135

60, 61, 89 652
6 Molecular Genetics of Schizophrenia Induced Pluripotent Stem Cells, Schizophrenia BYERLEY, CLONINGER, GEJMAN

R01MH059571

40, 41, 42, 43, 44, 45, 46, 47, 48, 49 1385
7 Genetics of Early-Onset Major Depression Depression DEPAULO, WEISSMAN, ZUBENKO

R01MH060912

80, 81, 82, 83, 84, 85 2238
8 Genetic Analysis of Bipolar Disorder Bipolar Disorder PATO

R01MH058693

38 223
9 A study of Schizophrenia Schizophrenia BERMAN, WEINBERGER

NA

39 830
10 Collaborative Linkage Study in Autism Autism FOLSTEIN

R01MH055135

62 4
12 Genetic Analysis of Psychosis Schizophrenia PATO

R01MH052618

33 233
13 Genetics of Schizophrenia in Latino Populations Schizophrenia ALMASY, CANIVE, ESCAMILLA, GLAHN, NICOLINI, RAVENTOS

R01MH060881

17, 53, 54, 55, 56, 57, 58, 59 1241
14 Molecular Genetics of Infantile Autism Autism RISCH

R01MH052708

63 563
15 A Neurobehavioral Family Study of Schizophrenia Schizophrenia NIMGAONKAR

R01MH042191

70, 71 645
16 Collaborative OCD Genetic Study Obsessive-Compulsive Disorder NESTADT

R01MH050214

164, 64, 65, 66, 67, 68, 69 1351
17 CLINICAL ANTIPSYCHOTIC TRIALS OF INTERVENTION EFFECTIVES (CATIE); Replication of Schizophrenia Associations in CATIE Alzheimer's Disease, Schizophrenia LIEBERMAN, SULLIVAN

N01MH090001, R01MH074027
NDA: 2081 , 2159

75, 76 926
18 Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Depression RUSH

N01MH090003
NDA: 2148

77 1942
19 Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD) Bipolar Disorder, Controls NIMGAONKAR

N01MH080001
NDA: 2147

14, 78, 86, 88 2365
20 Treatment of Adolescents with Depression (TADS) Depression MARCH

contract RFP-NIH-NIMH 98-DS-0008
NDA: 2145

79 171
21 AGRE; A Genomewide Search for Autism Susceptibility Loci Autism GESCHWIND

R01MH064547

72, 74 3909
22 Project among African-Americans to explore risks for schizophrenia (PAARTNERS) Schizophrenia GO, NIMGAONKAR

R01MH066181

101, 102, 103, 104, 105, 106, 107, 108, 109 1739
23 Genetic Susceptibility in Schizophrenia Controls, Schizophrenia NIMGAONKAR

R01MH056242

73 489
24 Genetics of Anorexia Nervosa Eating Disorders BERRETTINI, HALMI, KAYE

R01MH066122

110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120 1208
25 International Multi-Center ADHD Genetics Project (IMAGE) Attention-Deficit Hyperactivity Disorder FARAONE

R01MH062873

19, 90, 91, 92, 93, 94, 95, 96, 97, 98, 99 4959
27 The Genetics of Endophenotypes and Schizophrenia (COGS) Schizophrenia BRAFF

R01MH065571

122, 123, 124, 125, 126, 127, 128, 253, 254, 255, 256, 257 1347
28 A study of ADHD (CHOP) Attention-Deficit Hyperactivity Disorder ELIA

5K23MH066275-05

130 1500
29 Molecular Genetics of Schizophrenia Controls, Induced Pluripotent Stem Cells, Schizophrenia BYERLEY, GEJMAN

R01MH059571

139, 140, 141, 142, 143, 144, 145, 146, 147, 148, 149, 150 9049
30 A study of Autism Autism RODIER

1P50HD055753-01, 5U19HD035466-08
NDA: 1853

158 50
31 A study of Autism Autism RODIER

1P50HD055753-01, 5U19HD035466-08
NDA: 1853

151 79
32 A study of Autism Autism SZATMARI

152 483
33 Longitudinal Study of Language and Theory of Mind in Autism Autism TAGER-FLUSBERG

P01DC003610, 3U19DC003610-08S1

153 210
34 Neurobiology and Genetics of Autism Autism DAWSON

U19HD035465
NDA: 1853

154 214
35 Molecular and Genetic Epidemiology of Autism Autism PERICAK-VANCE

R01MH080647

155 1221
36 A study of Autism Autism MCINNES

156 310
37 Research Units of Pediatric Psychopharmacology (RUPP-PI) Autism MCDOUGLE

U10MH066766
NDA: 2349

157 133
39 New Jersey Language & Autism Genetics Study (NJLAGS) Autism BRZUSTOWICZ

RC1MH088288
NDA: 1932 , 2933

161 648
40 Bipolar Genome Study (BiGS) Bipolar Disorder BERRETTINI, BYERLEY, CORYELL, MCINNIS, NURNBERGER

P50CA89392, K02DA021237

170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181 3934
41 The Development of the Siblings of Children with Autism: A Longitudinal Study; Heterogeneity in Autism Biomarkers, Trajectories and Treatments Autism BOOKHEIMER, GESCHWIND

P50HD055784
NDA: 10 , 1854 , 2026

700, 701, 702, 703, 704, 706, 707 438
42 A Genome Wide SNP Association Study: Schizophrenia Schizophrenia FALLIN, PULVER

R01MH068406

185 197
43 A study of ADHD Attention-Deficit Hyperactivity Disorder TODD, TODOROV

132 800
44 Genetic Analysis of 15q11-q13 in Autism Autism SUTCLIFFE

R01MH061009

165 362
45 Detection of Susceptibility Genes in ADHD Attention-Deficit Hyperactivity Disorder LOO

5R01MH058277-10

135 1200
48 Genetic Linkage and Association in Bipolar Disorder / Amish Mennonite Bipolar Genetics Study (AmBiGen) Bipolar Disorder DEPAULO, MCMAHON

PART1: Application Number NA_00038551 (JH IRB #) / PART 2: ZIA MH002843-11 DIRP

186, 187, 188 471
49 Genetics of Bipolar Disorder in Latino Populations Bipolar Disorder ALMASY, ESCAMILLA, GLAHN, RAVENTOS

R01MH069856

190, 191, 192, 193, 194, 195, 196, 197 2679
50 Genetics of Autism Intermediate Phenotypes Autism COON

R01MH069359

200, 201 1778
51 A study of ADHD Attention-Deficit Hyperactivity Disorder MARTIN, TODD, TODOROV

5R01MH071629-02

121 1700
52 Genetics of Early-Onset Major Depression (GenRED II) Depression CORYELL, DEPAULO, WEISSMAN

R01MH060912

280, 281, 282, 283, 284, 285, 286 1902
55 Adolescents at High Risk for Familial Bipolar Disorder Bipolar Disorder MCINNIS, NURNBERGER

R01MH068009

750, 751, 752, 753 325
56 Clinical and Immunological Investigations of Subtypes of Autism Autism AMARAL, ROGERS, THURM, VAN DE WATER

Clinical and Immunological Investigations of Subtypes of Autism

163, 208 1188
58 Genetics of Brain Structure and Function Brain Function BLANGERO, GLAHN

R01MH078111, R01MH078143

136 1480
59 High-Density Genome-Wide Association Study of Schizophrenia in Large Dutch Sample Schizophrenia OPHOFF

R01MH078075

100 331
60 A study of Autism Autism PIVEN

167 276
61 Molecular Genetic Studies of Human Anxiety Disorder Fear & Anxiety HEN

P01MH60970

137 380
62 Molecular Genetic Studies of Human Anxiety Disorder Fear & Anxiety FYER

P01MH60970

138 197
63 Interdisciplinary Studies of Insistence on Sameness in Autism Spectrum Disorders Autism COOK

P50HD055751
NDA: 1

168 515
64 Center for Genomic and Phenomic Studies in Autism Autism LAJONCHERE, ROULLET, SOHL

5U24MH081810, R01MH081754
NDA: 7

202, 203, 204, 205, 206, 207, 229 1263
65 Trio Autism Simplex Collection (TASC) Autism GESCHWIND, NURNBERGER, SZATMARI

Funded by Autism Speaks
NDA:

210, 211, 212, 213, 214, 215, 216, 217, 218, 219, 220, 221 3384
66 OCD Collaborative Genetics Association Study Obsessive-Compulsive Disorder FYER, NESTADT

R01MH071507

240, 241, 242, 243, 244 3419
67 Population Based Mapping of Schizophrenia Genes Schizophrenia ESCAMILLA, RAVENTOS

R01MH061884

129 523
68 Biological Prediction of Psychosis Susceptibility among Adolescent Cannabis Users Schizophrenia DELISI

R01DA021576

131, 18 73
69 Biological and Information Processing Mechanisms Underlying Autism Autism MINSHEW

P50HD055748
NDA: 6

209 263
70 Consortium for Neuropsychiatric Phenomics Research Domain Criteria BILDER

1UL1RR024911
NDA: 2499

182 1096
71 Bipolar Endophenotypes in Population Isolates Bipolar Disorder FREIMER

R01MH075007

198, 199 546
72 Preventing Relapse in Schizophrenia: Oral Antipsychotics Compared To Injectables: Evaluating Efficacy (PROACTIVE) Schizophrenia KOPELOWICZ, MANSCHRECK, MILLER

U01MH070010
NDA: 2154

261 186
73 Combining Medications to Enhance Depression Outcomes (CO-MED) Depression KORNSTEIN, LEUCHTER, PRESKORN, ZISOOK

N01 MH090003-02
NDA: 2158

287 478
74 Examination of Genetic and GxE Effects in the Family and Community Health Studies (FACHS) Depression PHILIBERT

R01MH080898

133, 134 800
75 Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial (LiTMUS) Bipolar Disorder IOSIFESCU, OSTACHER, THASE

Lithium Use for Bipolar Disorder: A Randomized Controlled Effectiveness Trial
NDA: 2289

189 192
76 Genomic Psychiatry Cohort (GPC) Controls, Schizophrenia BROMET, ESCAMILLA, MALASPINA, PATO

R01MH104964

251, 262, 263, 264, 265, 266, 267, 268, 269, 271, 351, 352, 844, 869 20292
77 International Cohort Collection for Bipolar Disorder Bipolar Disorder, Controls BROMET, ESCAMILLA, MALASPINA, SMOLLER

R01MH085542

252, 270, 272, 273, 274, 275, 304, 305, 306, 307, 308, 309, 310, 311, 312, 845, 868 9377
78 Netherlands Twin Register Netherlands Twin Register BARTELS, BOOMSMA, DE GEUS

R01D0042157-01A

169 8540
79 AUTISM GENETICS: HOMOZYGOSITY MAPPING AND FUNCTIONAL VALIDATION Autism DEMMER, KUNKEL, WALSH

R01MH085143, R01MH083565
NDA: 1951 , 2029

222, 223, 224, 225, 226, 227 1064
80 Suicidal Behavior in Mood Disorders: Genes and Intermediate Phenotypes Suicide MANN, RUJESCU, TURECKI

R01MH082041

288, 289, 290 181
81 Predictors and Mechanisms of Conversion to Psychosis (NAPLS) Schizophrenia ADDINGTON, CORNBLATT

R01MH082004
NDA: 2275

291, 292, 293, 294, 295, 296, 297, 298 960
82 Expanding Rapid Ascertainment Networks of Schizophrenia Families in Taiwan Schizophrenia GLATT, TSUANG

R01MH085560; R01MH085521

183 9083
83 Incomplete Response in Late Life Depression: Getting to Remission Depression MULSANT, TSUANG

R01MH083660

277, 278, 279 437
84 Predictors of Antidepressant Treatment Response: The Emory CIDAR; Predictors of Treatment Response, Relaps, and Recurrence in Major Depression Depression CRAIGHEAD, MAYBERG

P50MH077083, R01MH080880

276 231
85 Language and Risk in Schizophrenia Schizophrenia DELISI

R21MH083205

260 90
86 Autism-Spectrum Disorder Genetics Autism HAINES, PERICAK-VANCE

Autism-Spectrum Disorder Genetics

230 200
87 Emory-MSSM-GSK-NIMH Collaborative Mood and Anxiety Disorders Initiative Post-traumatic Stress Disorder MAYBERG

U19MH069056

299, 300, 313, 314 108
88 Depression Susceptibility Genes and Networks: Expression, eQTL and GWAS Analysis Depression LEVINSON

RC2MH089916

621 463
90 A genome-wide association study of Schizophrenia in Ireland Schizophrenia CORVIN, RILEY

R01MH083094

301, 302 562
91 Whole-genome sequencing for rare highly penetrant gene variants in schizophrenia Schizophrenia GOLDSTEIN

RC2MH089915

258, 259 226
92 Family-Based Genome-Wide Methylation Scan in Neurocognition and Schizophrenia Induced Pluripotent Stem Cells GUR, NIMGAONKAR

RC2MH089973

320, 321, 322, 323 130
93 Identifying Intermediate Phenotypes for Compulsive Hoarding Obsessive-Compulsive Disorder MATHEWS

R21MH087748

245 120
94 Common and rare variant genetic screens for clozopine-induced agranulocytosis (CIAC) Schizophrenia SULLIVAN

R01MH080403

324, 325, 326 270
95 Abnormal Sterols in ASD and NIMH HGI Repository Expansion (4000) Autism TIERNEY

RC2MH090027

232, 233, 234 400
96 Olanzapine Versus Placebo in Outpatients with Anorexia Nervosa Eating Disorders ATTIA, STEINGLASS

R01MH085921

395, 396, 397, 398, 399 73
98 The Effects of Estradiol on Genetic Risk for Disordered Eating during Puberty Eating Disorders KLUMP

R01MH092377

246 362
99 Brain-Behavior and Genetic Studies of the 22q11DS 22Q11.2DS GUR

U01MH087626

247, 248 358
100 A Longitudinal Imaging Study of Infants at Risk for Autism Autism BOTTERON, PIVEN

R01HD055741
NDA: 19 , 2027

236, 237, 238, 239 0
101 Pharmacogenomics of Mood Stabilizer Response in Bipolar Disorder Induced Pluripotent Stem Cells BERRETTINI, CORYELL, KELSOE, LOHOFF, MCINNIS, NIEVERGELT, NURNBERGER, ODEGAARD

U01MH092758
NDA: 2497

420, 421, 422, 423, 424, 425, 426, 427, 428, 429 10
102 Genomic Studies of Bipolar Disorder in a Large Cohort from the Netherlands Bipolar Disorder OPHOFF

R01MH090553

430, 431 2500
103 Efficacy and Tolerability of Riluzole in Treatment-Resistant Depression Depression FAVA, MATHEW, SANACORA, ZARATE

5R01MH085055, 5R01MH085054, 5R01MH085050

622, 623, 624, 625 275
104 Comparison of Long-Acting Injectable Medications for Schizophrenia (ACLAIMS) Schizophrenia BYERLEY, CAROFF, JARSKOG, KONICKI, LAMBERTI, STROUP

R01MH081107
NDA: 2247

327, 328, 329, 330, 331, 332, 333, 334, 335, 336, 337, 338, 339, 340, 341, 342, 343, 344, 345, 346, 347 174
105 Establishing Moderators/Biosignatures of Antidepressant Response- Clinical Care (EMBARC) Depression MCGRATH, TRIVEDI, WEISSMAN

U01MH092221, U01MH092250
NDA: 2199

626, 627, 628, 629 400
106 Collaborative Genomic Studies of Tourette Disorder Tourette Syndrome BROWN, COFFEY, GILBERT, GRICE, HEIMAN, KUPERMAN, STATE, TISCHFIELD, ZINNER

R01MH092293
NDA: 2958

600, 602, 603, 604, 605, 606, 607, 608, 609, 610, 611, 612, 613, 614, 615, 616, 617, 618, 619, 620 3043
107 RAISE - Early Treatment Program (ETP) Genetics Schizophrenia KANE

HHSN-271-2009-00019C
NDA: 2249

350 400
108 Sustaining Remission of Psychotic Depression Depression FLINT, MEYERS, ROTHSCHILD, WHYTE

5U01MH062518, 5U01MH062624, 5U01MH062565, 4U01MH062446

630, 631, 632, 633 177
109 Discovery Science of Human Brain Function Across the Lifespan Brain Function MILHAM

R01MH094639

303 331
110 D-Cycloserine Augmentation of CBT for Pediatric OCD Obsessive-Compulsive Disorder GELLER, STORCH

R01MH093402, R01MH093381
NDA: 2496

249, 250 116
111 Biomarkers for Psychosis in Velo-cardio-facial Syndrome 22Q11.2DS KATES

R01MH064824

394 64
112 The Genetics of Autism: Epilepsy as a Biomarker Autism DEVINSKY

The Genetics of Autism: Epilepsy as a Biomarker

724, 725, 740 388
113 Identifying Biomarkers for Post-Partum Depression in African-American Women Depression RUBINOW, SULLIVAN

R01MH095992

634 2000
114 Mapping the Human Connectome: Structure, Function, and Heritability Brain Function VAN ESSEN

U54MH091657
NDA: 2825

400 1209
115 Exploring the Neuronal Phenotype of Autism Spectrum Disorders Using Induced Pluri Induced Pluripotent Stem Cells, Phelan-McDermid Syndrome DOLMETSCH, HALLMAYER

R33MH087898

726, 734 188
116 Cellular and genetic correlates of increased head size in autism spectrum disorder Autism, Induced Pluripotent Stem Cells VACCARINO

R33MH087879
NDA: 1201 , 2424

727 74
117 Autism iPSCs for Studying Function and Dysfunction in Human Neural Development Autism, Induced Pluripotent Stem Cells LORING

R33MH087925

728 4
119 Attaining and Maintaining Wellness in OCD Obsessive-Compulsive Disorder SIMPSON

R01MH045436, R01MH045404

401, 402 133
120 RDoC Constructs: Neural Substrates, Heritability, and Relation to Psychopathology Research Domain Criteria ZALD

R01MH098098
NDA: 2099

500 396
121 Depression (RAPID LFMS) Depression IOSIFESCU, PAPAKOSTAS, SANACORA

HHSN2712011000061

754, 755, 756, 757, 758, 759 90
122 Characterization of a Mendelian Form of Psychosis in a Population Isolate Schizophrenia ALMASY, GLAHN, RAVENTOS

R56MH097940

319 215
123 Acute Psychotherapy for Bipolar II Depression Bipolar Disorder SWARTZ

R01MH084831

432 38
124 Multi-pronged genetic studies of schizophrenia in an inbred population Schizophrenia NIMGAONKAR

R01MH093246

349 760
125 Analysis of Glutamatergic Neurons Derived from Patient Specific iPS Cells Induced Pluripotent Stem Cells LACHMAN

R33MH087840

392, 393 13
126 Autism (ACE Network) Autism CONSTANTINO, GESCHWIND, KLIN, MOLHOLM

R01MH100027
NDA: 2035

712, 718, 719, 720 1672
127 Target Identification and Validation for Negative Symptoms and Social Cognition in Schizophrenia: A Translational Study Induced Pluripotent Stem Cells, Schizophrenia HAHN

funded by Pfizer via University of Pennsylvania ? Pfizer collaborative alliance

717 8
128 A Comprehensive Approach To Identification of Autism Susceptibility Genes Autism GESCHWIND, LAJONCHERE

R01MH081754
NDA: 7

713, 714, 715, 716 343
129 Anorexia Nervosa Genetics Initiative (ANGI Project) Eating Disorders BULIK

Anorexia Nervosa Genetics Initiative (ANGI Project)

403, 404 5657
130 Genomics-Guided Characterization of iPS Cells from Common Mental Illnesses Induced Pluripotent Stem Cells HAGGARTY, PERLIS

R21MH093958, R33MH087896

433, 434 4
131 Chemical genomic approaches to neurobiology of DISC1 Bipolar Disorder, Induced Pluripotent Stem Cells, Schizophrenia TSAI

R01MH091115

317, 318 20
132 NIMH DIRP Protocol 03-M-0035 Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-Up for Childhood Onset Psychiatric Disorders Induced Pluripotent Stem Cells RAPOPORT

1ZIAMH002581

499, 502 228
133 Biomarker Discovery in Anorexia Nervosa II Eating Disorders BARDONE-CONE, BULIK

R01MH095860

405 169
134 Genetic Study of Trichotillomania Obsessive-Compulsive Disorder KEUTHEN, SCHARF

Funded by the Trichotillomania Learning Center (TLC).

508, 788, 790 419
135 Multimodal Developmental Neurogenetics of Females with ASD Autism BOOKHEIMER, PELPHREY

R01MH100028
NDA: 2021

470, 471, 472, 473 857
136 Integrative Molecular and Phenotype Analysis of 22q11.2 Deletion Syndrome 22Q11.2DS, Induced Pluripotent Stem Cells, Research Domain Criteria, Schizophrenia HALLMAYER

R01MH100900
NDA: 2605

355 198
137 Genomics of Schizophrenia in the South African Xhosa (SAXI) Schizophrenia KING, STEIN, SUSSER

U01MH096754-01A1

356 2200
138 Identification of rare variants of OCD Obsessive-Compulsive Disorder NESTADT

R01MH097993-01A1

406 196
139 Addition of OCD to the Genomic Psychiatry Cohort Obsessive-Compulsive Disorder PATO

R01MH103657

407, 417, 783, 787, 805, 822, 881 5000
140 Genome Sequencing in Extended Bipolar Pedigrees Bipolar Disorder FREIMER

3R01MH095454-02S1

435, 436 349
141 Genetic Analysis of High-Risk Utah Suicide Pedigrees Suicide COON

R01MH099134

315 3339
142 Psychosis and Affective Research Domains and Intermediate Phenotypes (PARDIP) Research Domain Criteria CLEMENTZ, KESHAVAN, PEARLSON, TAMMINGA

R01MH096913-01A1, R01MH096957-01A1, R01MH096900-01A1, R01MH096942-01A1
NDA: 2126

496, 497, 498 194
143 Modeling Anorexia Nervosa with Human Pluripotent Stem Cells Eating Disorders, Induced Pluripotent Stem Cells MUOTRI

R21MH093954-02

408 8
144 Modeling Autism with Human Pluripotent Cells Autism, Induced Pluripotent Stem Cells MUOTRI

1DP2OD006495

738 17
146 Induced Neuronal Cells: A Novel Approach to Study Neuropsychiatric Diseases Autism, Induced Pluripotent Stem Cells WERNIG

R01MH092931

741 8
147 Longitudinal Family/Molecular Genetic Study to Validate Research Domain Criteria Research Domain Criteria FARAONE, GLATT

1R01MH101519-01A1
NDA: 2103

501 2448
148 Identifying regulatory mutations that influence neuropsychiatric disease Schizophrenia GOLDSTEIN, PULVER

U01MH105670-01

357, 358, 359 235
149 Rapidly-Acting Treatments for Treatment-Resistant Depression (RAPID) Depression CUSIN, FAVA, IOSIFESCU, SANACORA

HHSN271201100006I
NDA: 2166

760, 761, 762, 763, 764, 765 100
150 The Genomics of Treatment-Resistant Psychotic Symptoms Schizophrenia EVANS, FARRELL, JOSIASSEN, SHAUGHNESSY, SULLIVAN

none

354 1000
151 Predictors and Mechanisms of Conversion to Psychosis (NAPLS3) Research Domain Criteria, Schizophrenia ADDINGTON, CANNON, CORNBLATT, MATHALON

2R01MH081902-06A1
NDA: 2275

486, 487, 488, 489, 490, 491, 492, 493, 494 711
152 Control and Reward Circuits as Targets for Repetitive Thoughts and Behaviors Obsessive-Compulsive Disorder MARSH

R01MH104648-01

409 66
154 FAST MAS KOR Phase 2a Research Domain Criteria LISANBY, NURNBERGER, SANACORA

HHSN2712011000061
NDA: 2277

410, 411, 412, 413, 414, 415 78
155 Gene Networks Influencing Psychotic Dysconnectivity in African Americans Schizophrenia GLAHN

R01MH106324-01

360 750
156 Transferred from Coriell Collection Bipolar Disorder, Schizophrenia GERSHON

735, 736 2000
157 Neuroinflammation and Aggression (RDoC) Research Domain Criteria COCCARO

1R01MH104673-01

503 150
158 Modeling schizophrenia using iPSC neurons Induced Pluripotent Stem Cells BRENNAND

Supported by private funds

361 11
159 A chimeric brain model to study human neurological diseases Autism, Induced Pluripotent Stem Cells MUOTRI

1R21MH10777-01

742 6
160 Contrasting causal microRNAs in forebrain and midbrain COS hiPSC neural cells Induced Pluripotent Stem Cells BRENNAND

5R01MH101454-02

504 22
161 iPSC-derived human cortical interneurons as developmental model of Schizophrenia Induced Pluripotent Stem Cells, Schizophrenia CHUNG

1 R01 MH107884-01

362, 363, 807 24
162 Bipolar-Schizophrenia Network for Intermediate Phenotypes 2 (BSNIP2) Bipolar Disorder, Schizophrenia TAMMINGA

2R01MH077851-05A1
NDA: 2165

364, 365, 366, 367, 368 3600
163 Neuropsychiatric Genome-Scale and RDoC Individualized Domains (N-GRID) Induced Pluripotent Stem Cells KOHANE, PERLIS

5P50MH106933

416 134
164 The Autism Biomarkers Consortium for Clinical Trials (ABC-CT) Autism MCPARTLAND

1U19MH108206-01
NDA: 2288

474, 475, 476, 477, 478 531
165 Neural development of human induced pluripotent stem cells from schizophrenia patients Induced Pluripotent Stem Cells, Schizophrenia SONG

R21/R33MH087874

369 4
166 Juvenile Onset Schizophrenia iPSCs Induced Pluripotent Stem Cells, Schizophrenia FINDLING, MILLER, TESAR

R21/R33MH087877

370 13
167 Biomarker Assessment of Pomaglumetad on Glutamate Targets: Proof of Clinical Mechanism of Action (POCM) Controls LIEBERMAN

HHSN271201200007I, HHSN27100003
NDA: 2862

793, 794, 795, 796 91
168 Mapping the Human Connectome During Typical Aging Brain Function ANCES, BOOKHEIMER, SALAT, TERPSTRA, VAN ESSEN

U01 AG052564
NDA: 2847

797, 798, 799, 800 1223
169 Genomics of Postpartum Depression. Depression MELTZER-BRODY, SULLIVAN

There is no grant number for this study

669, 769 25000
171 Genetic Contributions of Negative Valence Systems to Internalizing Pathways Research Domain Criteria ROBERSON-NAY

R01MH101518
NDA: 2136

771 307
172 A Clinical Study to Establish a Metabolic Biomarker-Based Test to Diagnose Autism Spectrum Disorder in Early Childhood Autism BURRIER

1R44MH107124-01
NDA:

772, 773, 774, 775, 776, 777, 784, 786 367
174 The Role of Dysmyelination in Cognitive Impairment of Psychotic Disorders Schizophrenia LAZAR

1R01MH108962-01
NDA: 2575

779 210
175 Neurobiology of Autism With Macrocephaly Autism, Induced Pluripotent Stem Cells VACCARINO

R01MH109648
NDA: 2424

780 62
178 Human Connectome Project for Early Psychosis; Human Connectome Project for Early Psychosis iPSC bank. Brain Function BREIER, SHENTON

U01MH109977; NHMRC Investigator Grant APP1175754
NDA: 2914 , 3179

1031, 791, 792 205
179 Ultra High Field Strength MRI and MRS Study of Bipolar Disorder in Adolescents Bipolar Disorder BLUMBERG

R21MH108940

789 16
180 Mapping the Human Connectome During Typical Development Brain Function BARCH, BOOKHEIMER, SOMERVILLE, THOMAS, VAN ESSEN

U01MH109589
NDA: 2846

801, 802, 803, 804 1243
181 Development of New therapeutic targets for patients with Bipolar disorder who are resistant to conventional psychotropic medications using induced Pluripotent Stem Cells (iPSC) Bipolar Disorder, Induced Pluripotent Stem Cells CHUNG, GAGE

There is no grant number associated with this study

806 20
182 Systematic Functional Interpretation of Regulatory Variants in Schizophrenia Induced Pluripotent Stem Cells, Schizophrenia DUAN, PENZES

R01MH106575; R21MH102685

808, 809, 836 20
183 Multimodal analysis of high-risk psychosis mutations in induced neuronal cells Induced Pluripotent Stem Cells, Schizophrenia LEVINSON, SUDHOF, WERNIG

U19MH104172

810, 811 20
184 iPSC-based platform development for major psychiatric disorder modeling and discovery Bipolar Disorder, Induced Pluripotent Stem Cells ALDA, BANG, CHEN, GAGE, MCINNIS, OSHEA, SONG

U19MH106434
NDA: 3035

812, 813 34
185 Alzheimer?s Disease Connectome Project Alzheimer's Disease, Brain Function BENDLIN, LI

UF1AG051216

814, 815 300
187 Healthy Brain Network Brain Function MILHAM

Not associated with an active grant

818 6500
188 Aging and Emotion Regulation Brain Circuitry in Bipolar Disorder Bipolar Disorder BLUMBERG

R01MH113230
NDA: 2695

819 79
189 Genetics of Severe Mental Illness -Colombia Schizophrenia BEARDEN, FREIMER, LOPEZ-JARAMILLO

R01MH113078
NDA: 3805

820 9204
190 MicroRNA Dysregulation in Psychiatric Disorders and Cognitive Dysfunction. Induced Pluripotent Stem Cells, Schizophrenia GOGOS, MARKX

R01MH097879
NDA: 2829

821 12
191 Longitudinal Assessment of Posttraumatic Syndromes. Research Domain Criteria JOVANOVIC, KESSLER, KOENEN, MCLEAN, PALLIN, PEARSON, SERGOT

U01MH110925
NDA: 2526

823, 824, 825, 826, 827, 828, 829, 830, 831, 832, 833, 841, 842, 843, 846, 847, 865, 866, 867, 872, 873, 874, 875, 876, 877, 878, 879, 880 3900
192 Modeling the Human Neuronal Phenotype of the Schizophrenia-Associated 3q29 Deletion Induced Pluripotent Stem Cells, Schizophrenia MULLE

R01MH110701
NDA: 2614 , 3126

834 107
193 Binge Eating Genetics INitiative (BEGIN) Eating Disorders BULIK

na
NDA: 3361

835 5000
194 Dimensional Connectomics of Anxious Misery Fear & Anxiety SHELINE

U01MH109991
NDA: 3161

837 250
195 Large-scale reprogramming and expression analysis of patient-derived neural cells in schizophrenia Induced Pluripotent Stem Cells, Schizophrenia BRENNAND, BUXBAUM

R01MH111679
NDA: 5081

838 183
196 Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies. Controls CHUNG

n/a (Protocol number 17-M-0181)
NDA: 2843

839 2000
197 A conserved transcriptional cascade involved in brain overgrowth, social behavior and autism. Autism, Induced Pluripotent Stem Cells WYNSHAW-BORIS

R01MH113106

840 12
199 The GEN-SCRIP Study (GENetics of SChizophRenia in Pakistan) Schizophrenia KNOWLES

R01MH112904

854 17000
200 Mechanisms of Circuit Failure and Treatments in Patient-derived Neurons in Autism Autism, Induced Pluripotent Stem Cells MORROW

R01MH105442

857 15
201 Cellular, molecular, and functional imaging approaches to understanding early neurodevelopment in autism. Project 3: Biological substrates of risk and resilience using patient-derived stem cells Autism, Induced Pluripotent Stem Cells VACCARINO

P50MH115716
NDA: 2821

858 33
202 Genetic Characterization of Neurodevelopmental Disorders in African Populations (NeuroDev Africa) Brain Function ABUBAKAR, DONALD, ROBINSON

R01HD102975-01

859 6000
203 Collaborative Genomic Studies of Tourette Disorder: Phase II Induced Pluripotent Stem Cells, Tourette Syndrome BROWN, COFFEY, GILBERT, HEIMAN, HUYSER, KUPERMAN, WILLSEY, ZINNER

R01MH115958; R01MH115959; R01MH115960; R01MH115961; R01MH115962; R01MH115963; R01MH115993
NDA: 2958

600, 601, 602, 603, 604, 606, 608, 610, 611, 612, 614, 615, 616, 620, 861, 862, 863, 864, 883, 890, 968, 997 3000
204 Autism Genetics, Phase II: Increasing Representation of Human Diversity Autism GESCHWIND

R01MH100027-11
NDA: 2976

712, 718, 719, 720 1691
205 Hoarding disorder in older adults: cognition, etiology and functional impact. Obsessive-Compulsive Disorder MACKIN, MATHEWS

R01MH117114
NDA: 2995

870, 871 3500
210 Dissecting the effects of genomic variants on Neurobehavioral dimensions in CNVs enriched for neuropsychiatric disorders. Rare Genetic Syndromes GUR

U01MH119738-01; U01MH119737-01; U01MH119736-01; U01MH119758-01; U01MH119741-01; U01MH119739-01
NDA: 3228

884, 885, 886, 887, 888, 896 2000
212 Multimodal Developmental Neurogenetics of Females with ASD Autism PELPHREY

MH100028
NDA: 2021 & 2804

891, 892, 894, 895 400
213 Leveraging Rare Genetic Etiologies to Advance Knowledge and Treatment of Neuropsychiatric Disorders Rare Genetic Syndromes MARTIN

U01 MH119705
NDA: 3227

897, 898, 899 1233
214 Genetics of suicide death Suicide COON

R01MH122412
NDA: 3618

315 3500
215 Eating Disorder Genetics Initiative (EDGI) Eating Disorders BULIK

R01MH120170
NDA: 3310

900, 901, 902 11000
216 Latino Ancestry Genomic Psychiatry Cohort Bipolar Disorder, Controls, Schizophrenia BIGDELI, FANOUS, PATO

R01MH123451
NDA: 3701

903, 904, 918, 919 6000
217 African Ancestry Genomic Psychiatry Cohort - Phase II and Populations Underrepresented in Mental illness Association Studies (PUMAS) Bipolar Disorder, Controls, Schizophrenia BIGDELI, FANOUS, PATO

R01MH104964; U01MH125049
NDA: 3700 , 3805

1018, 352, 844, 869, 920 4000
218 The GEN-BLIP Study (GENetics of BipoLar Disorder In Pakistan) Bipolar Disorder KNOWLES

1R01MH123775-01
NDA: 3595

905 12000
219 Powering Genetic Discovery for Severe Mental Illness in Latin American and African Ancestries. Bipolar Disorder, Controls, Schizophrenia FREIMER, LOPEZ-JARAMILLO, OLDE LOOHUIS, OPHOFF

U01MH125042
NDA: 3805

1000, 906, 907, 908, 909, 998, 999 18900
221 Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations Brain Function BUCKLEY, FARMER, PAO, THURM

N/A. This study is supported via intramural funding.
NDA:

913 244
222 ProNET: Psychosis-Risk Outcomes Network Research Domain Criteria, Schizophrenia BEARDEN, KANE, WOODS

U01MH124639
NDA: 4366

1032, 1033, 1034, 1035, 1036, 1037, 1038, 1039, 1040, 1041, 1042, 1043, 1044, 1045, 1046, 1047, 1048, 1049, 1050, 1051, 1052, 1053, 1054, 1055, 1056, 1057, 914 1430
223 Trans-ancestry genomic analysis of obsessive-compulsive disorder Obsessive-Compulsive Disorder CROWLEY, IRRENO SOTOMONTE , STORCH

U01MH125062 and U01MH125050
NDA: 4066

1001, 1002, 1003, 1004, 1005, 1006, 1007, 1010, 1014, 1017, 1028, 1029, 1068, 916, 922, 923, 924, 925, 927, 928, 933, 934, 938, 944, 945, 947, 948, 949, 950, 952, 953, 955, 958, 959, 960, 966, 976, 977, 995 5000
224 The Price Foundation Genetic Studies of Anorexia and Bulimia Nervosa. Eating Disorders KAYE

Price Foundation

921, 973, 974 3741
225 Autism Biomarkers Consortium for Clinical Trials (ABC-CT): Confirmation Study and Pre-School Feasibility Study Autism MCPARTLAND

2U19MH108206-05
NDA: 3670

969, 970, 971, 972, 975 675
226 MRI Based Presymptomatic Prediction of ASD Autism PIVEN, PRUETT

1R01MH118362-01
NDA: 3221

978, 979, 980, 981, 982 1000
227 Breaking Through In OCD Genetics Obsessive-Compulsive Disorder STATE, WILLSEY

Foundation for OCD Research Grant #: 009395-2019-10-02

1019, 1020, 1067, 983, 984, 985, 986, 987, 988, 989, 990, 991, 992 5000
228 Molecular analysis of glutamatergic neurons derived from iPSCs containing PPM1D truncating mutations found in Jansen de Vries Syndrome Induced Pluripotent Stem Cells, Rare Genetic Syndromes LACHMAN

R21MH131740
NDA: 4725

1021 16
229 Investigation of Pitt-Hopkins Syndrome pathophysiology using a human model Autism, Induced Pluripotent Stem Cells MUOTRI

1R01MH123828-01A1

1022 12
230 Novel SETD5-based Molecular Mechanisms and Therapeutic Tools to Understand and Revert Neuronal Dysfunction Associated with Intellectual disability and Autism Autism, Induced Pluripotent Stem Cells GOREN, MUOTRI

R01MH127077

1023 6
231 Uncovering sex-specific differences in ASH1L-disease Autism, Induced Pluripotent Stem Cells LIU, LIZARRAGA

R21MH136643
NDA:

1027 10
232 Cellular consequences and convergent biology of schizophrenia-associated rare variants in the diverse GPC cohort Induced Pluripotent Stem Cells, Schizophrenia HART, MULLE, PANG, PATO

R01MH131296
NDA: 4442

1024 0
233 Neurodevelopment of Tourette syndrome Induced Pluripotent Stem Cells, Tourette Syndrome VACCARINO

1R01MH118453-01
NDA: 3187

1025 30
234 IBIS-iPSC: Organoid modeling of cortical surface area hyperexpansion in autism spectrum disorder Autism, Induced Pluripotent Stem Cells STEIN

1R01MH130441-01A1
NDA: 4747

1026 99
238 Genetic Architecture of Early-Onset Psychosis in Mexicans (EPIMex2) Bipolar Disorder, Schizophrenia ALMASY, GLAHN, NICOLINI

1R01MH133621-01
NDA: 4866

1030 5000
239 Predictors and Moderators of Long-Term Outcome of Persons at Clinical High Risk for Psychosis Schizophrenia CADENHEAD

R01MH123641
NDA: 4057

1058, 1059, 1060, 1061, 1062, 1063, 1064, 1065, 1066 250
240 Dysfunctional neurovascular interactions and neuroprogression in early-course psychosis: ex vivo investigation with patient-derived stem cells Induced Pluripotent Stem Cells KARMACHARYA, LIZANO

R01MH137205
NDA:

1069 40
Study Title Distributions PIs Grants Sites Subjects